The tower caught fire on 27 August 2000, killing three people. In addition, television and radio signals were disrupted around Moscow. The fire broke out approximately 98 metres (321 feet) above the observation platform and the Seventh Heaven restaurant, necessitating an evacuation of all visitors and staff from those locations. According to Russian news agencies, the evacuation was complete 90 minutes after the start of the fire. Due to the age of the electronic equipment — much of it was installed in the 1960s — and infrequent maintenance, the loss sustained was substantial. The only television station not affected was the private NTV station, but the government decreed that state channels took priority, and as such, the RTR TV channel began transmitting to several Moscow districts. 
On 1 July 2004, Austrian BASE jumper Christina Grubelnik struck the tower during her descent, receiving a concussion and losing consciousness. Her parachute snagged on a lower-level service platform and she was eventually rescued by Russian emergency services.   The incident was filmed, and the footage occasionally appears on "caught-on-camera" type reality TV shows.
On 25 May 2007, the tower once again caught fire. The BBC reported that this is not at this stage believed to be as serious as the 2000 fire and was isolated to a platform on the outside of the tower. All people inside the tower were evacuated and the fire was successfully extinguished, with no casualties.